Science fiction video game space flight simulation gameįirst-person shooter survival horror indie game Puzzle video game science fiction video game Puzzle video game platform game indie game Third-person shooter action-adventure game Video game virtual world Metaverse project GNU General Public License, version 2.0 or later Star_Wars:_Knights_of_the_Old_Republic_II_-_The_Sith_Lords Role-playing video game space opera video game Star Wars Knights of the Old Republic II: The Sith LordsĮn:Star Wars Knights of the Old Republic II: The Sith Lords Platform game side-scrolling video game stealth game action game Survival game action-adventure game sandbox game Ja:Sonikku za Hejjihoggu Tsū en:Sonic the Hedgehog 2 Turn-based strategy video game science fiction video game WDQS | PetScan | TABernacle | Find images Recent changes | Query: SELECT ?item WHERE GROUP BY ?item TitleĪssociation football management game association football video gameįirst-person shooter science fiction video game Manual changes to the list will be removed on the next update! This work was supported by German Science Foundation, the German Federal Ministry of Education and Research, and the Munich Center for Neuroscience.This list is periodically updated by a bot. "If you are open-minded and think it through, all of a sudden, you can see all the possibilities from one idea." "You have to have new ideas and new concepts to explore this is one of the ways science is driven," says Straka. Introducing oxygen-producing algae could help these tissues thrive and raise their survival rates, potentially reducing the need for live animals for experiments. Straka also envisions his research benefiting other laboratories that work with isolated tissues or organoids. The team's next step is to see whether the injected algae can survive inside living tadpoles and continue oxygen production without causing an immune response that wreaks havoc on the animals. While the researchers think their findings may someday lead to new therapies for conditions induced by stroke or oxygen-scarce environments, such as underwater and high altitudes, algae are far from ready to enter our blood circulation. "Working in principle doesn't really mean that you could apply it at the end, but it's the first step in order to initiate other studies." It was amazingly reliable and robust, and in my eyes, a beautiful approach," says Straka. "We succeeded in showing the proof of principle experiment with this method. The revived nerves also performed as well or even better than before oxygen depletion, showing that the researchers' method was quick and efficient. However, illuminating the tadpole head restarted the neural activity within 15 to 20 minutes, which is about two times faster than replenishing the bath with oxygen without the algae. As the researchers depleted oxygen from the bath, the nerves ceased firing and fell silent. Shining light on these tadpoles prompted both algae species to pump out oxygen to nearby cells.Īfter distributing algae to the brain, the researchers isolated the tadpole's head and placed it in an oxygen bubble bath with essential nutrients that would preserve the functioning of the cells, allowing the team to monitor neural activity and oxygen levels. With each heartbeat, the algae inched through blood vessels and eventually reached the brain, turning the translucent tadpole bright green. To explore the possibility, the team injected green algae ( Chlamydomonas renhardtii) or cyanobacteria ( Synechocystis) into tadpoles' hearts. In nature, algae live harmoniously in sponges, corals, and anemones, providing them with oxygen and even nutrients. ![]() ![]() Straka was studying oxygen consumption in tadpole brains of African clawed frogs ( Xenopus laevis) when a lunch conversation with a botanist sparked an idea to combine plant physiology with neuroscience: harnessing the power of photosynthesis to supply nerve cells with oxygen. "For many people, it sounds like science fiction, but after all, it's just the right combination of biological schemes and biological principles." "The algae actually produced so much oxygen that they could bring the nerve cells back to life, if you will," says senior author Hans Straka of Ludwig-Maximilians-University Munich.
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